🧬 Tirzepatide (Research Use Only)
Tirzepatide is a synthetic dual incretin receptor agonist peptide. It is designed to activate both:
- GLP‑1 (Glucagon‑Like Peptide‑1) receptors – enhancing insulin secretion, slowing gastric emptying, and reducing appetite.
- GIP (Glucose‑Dependent Insulinotropic Polypeptide) receptors – supporting insulin regulation, lipid metabolism, and amplifying GLP‑1 effects.
This dual mechanism is being studied for its potential to deliver superior metabolic outcomes compared to single‑pathway incretin agonists.
Research Applications
- Type 2 Diabetes: Investigated for improving glycemic control and reducing HbA1c.
- Obesity & Weight Management: Clinical studies show significant reductions in body weight, often exceeding results from GLP‑1 agonists alone.
- Cardiometabolic Health: Research explores effects on blood pressure, lipid profiles, and cardiovascular risk markers.
- Liver & Metabolic Disorders: Potential benefits in non‑alcoholic fatty liver disease (NAFLD) and insulin resistance syndromes.
Key Research Findings
- Weight Reduction: Trials report average weight loss of 15–20% over 72 weeks.
- Glycemic Control: HbA1c reductions of up to 2.3 percentage points in Type 2 diabetes patients.
- Cardiovascular Outcomes: Improvements in blood pressure, cholesterol, and waist circumference observed in ongoing studies.
- Pharmacokinetics: Approximate half‑life of 5 days, supporting once‑weekly dosing in research protocols.
⚠️ Important Notes
Compliance & Usage Notes
- Research Use Only (RUO): Tirzepatide provided here is strictly intended for laboratory research.
- Investigational Status: While FDA‑approved for Type 2 diabetes under the trade name Mounjaro, its broader applications (obesity, cardiometabolic disorders) remain under investigation.
- Not for Human Consumption:
- Compliance Reminder: This compound is not a therapeutic or consumer product; it is provided exclusively for controlled research purposes.
Specifications
| Molecular Weight | ~4813.45 g/mol |
| Purity | ≥99% (HPLC) |
| Physical Form | Lyophilized powder |
| Storage | -20°C, keep away from light and moisture |
Research Applications
- Glucose metabolism and insulin sensitivity studies
- Appetite regulation pathway research
- Dual incretin receptor signaling mechanisms
- Metabolic syndrome modeling
Disclaimer: This product is intended for laboratory and research use only. Not for human or animal consumption. All handling should be conducted by qualified researchers in accordance with applicable regulations.
Certificate of Analysis
Every batch of Tirzepatide sold by DPK is independently tested by a third-party laboratory. The Certificate of Analysis (COA) confirms identity, purity (≥99% via HPLC), and the absence of heavy metals and microbial contamination.
Lab Test Results
janoshik.com/tests/73294-Tirzepatide_10mg_SI45YMRYAQGQ
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